An 8-month-old male infant with bacterial respiratory infection

Friday, 16 March 2012

Question NO 6

An 8-month-old male infant is admitted to the hospital because of a
bacterial respiratory infection. The infant responds to appropriate antibiotic
therapy, but is readmitted several weeks later because of severe otitis
media. Over the next several months, the infant is admitted to the hospital
multiple times for recurrent bacterial infections. Workup reveals extremely
low serum antibody levels. The infant has no previous history of viral or
fungal infections. The most likely diagnosis for this infant is


a. Isolated IgA deficiency
b. Chronic granulomatous disease
c. DiGeorge’s syndrome
d. Wiskott-Aldrich syndrome
e. X-linked agammaglobulinemia of Bruton

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